Ownership

Ownership

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 32 1.74 5.19 1,526,038
Mutual Fund 11 0.81 2.60 733,780
Insider 10 0.44 1.77 521,640

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 20 2.78 12.46 3,663,903
Sellers 11 -0.48 1.77 -519,812
Net 2.31 10.69 3,144,091

Concentration

Value ($MM) % O/S Shares
Total Inst. 9.46 35.50 10,440,483
Top 10 Inst. 9.01 34.06 10,016,353
Top 20 Inst. 9.39 35.27 10,372,008
Top 50 Inst. 9.46 35.50 10,440,483

Style

Holders Value ($MM) % Inst Shares Shares
Growth
Aggressive Growth -- --
Core Growth 7 0.14 0.43 126,325
Growth 1 -- -- 5
Income
Income Value -- --
Yield 1 -- 0.01 1,500
Index 5 0.94 2.81 825,067
Other 11 0.64 1.91 560,174
Broker Dealer 3 0.01 0.02 6,121
GARP 1 -- -- 951
Hedge Fund 7 0.63 1.88 553,102
Specialty -- --
Value 4 0.01 0.03 9,516
Core Value 2 -- 0.01 4,156
Deep Value 2 0.01 0.02 5,360

Location: Global Region

Holders % O/S Shares Share Value
Asia / Pacific 2 20.59 6,055,952 5,551,289
North America 40 14.53 4,272,730 3,780,692
Europe 3 0.38 111,801 127,453

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Lee's Pharmaceutical Holdings Ltd. 4,816,864 16.38 3,458,487 4/29/22
Panacea Venture Healthcare Fund I LP 2,336,853 7.95 -- 4/29/22
Center Laboratories Inc 1,239,088 4.21 -- 12/30/21
The Vanguard Group, Inc. 551,274 1.87 -119,207 3/31/22
Huang (James Z) 291,281 0.99 -- 4/29/22
Renaissance Technologies LLC 234,446 0.80 18,946 3/31/22
Kepos Capital LP 165,000 0.56 -- 3/31/22
Geode Capital Management, L.L.C. 158,747 0.54 -- 3/31/22
Two Sigma Investments, LP 112,300 0.38 -24,400 3/31/22
SEB Investment Management AB 110,500 0.38 -- 3/31/22

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Total Stock Market Index Fund 397,013 1.35 -- 3/31/22
Vanguard Extended Market Index Fund 133,554 0.45 -- 3/31/22
Fidelity Extended Market Index Fund 131,008 0.45 -- 3/31/22
iShares Micro-Cap ETF 44,338 0.15 -262 4/30/22
Fidelity NASDAQ Composite Index Fund 19,030 0.06 -- 3/31/22
Vanguard Balanced Index Fund 14,800 0.05 -- 3/31/22
Fidelity Series Total Market Index Fund 8,372 0.03 -- 3/31/22
Vanguard US Equity Index Fund 5,907 0.02 -- 2/28/22
1290 VT Micro Cap Portfolio 4,060 0.01 -- 3/31/22
Blackstone Alternative Multi-Strategy Fund 1,500 0.01 1,500 12/31/21

* Insider values reflect direct beneficial ownership.

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